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These symptoms require medical assessment to rule out other underlying conditions

The extracted data included study characteristics (author, publication year, study design, and sample size), participant demographics and baseline characteristics (country, percentage of female participants, mean age, and population/diagnosis), intervention details (type of AOM, dosage, duration, route of administration, and frequency of administration), and information on which outcome metrics were reported

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Western blotting data indicated that GHK-Cu-liposomes may upregulate CDK4 and CyclinD1, proteins that govern the G1/S transition